Our Mission

Our mission is to significantly accelerate innovation cycles in biopharmaceutical industry by combining proprietary scaling lab technology using protein crystals and machine learning.

Our Technology

CrystalsFirst proprietary technology realizes the potential of 3D-models for structure-guided drug design and meets the high demand for bio-structural data to
 
  • tailor the compounds for high affinity, selectivity, safety, and efficacy,
  • identify new modes of action for drug candidates,
  • enter design paths of allosteric modulators,
  • tap into unexplored IP and chemical spaces,
  • and increase efficiency of the drug pipeline.
 
The core technology SmartSoak® is integrated into an in-house modular ecosystem, which provides more specifically
 
  • hit identification and optimization in challenging projects,
  • faster cycle times from ligand to 3D structure,
  • higher throughput of 3D-models for structural insight,
  • flexible application of compound libraries in crystallographic screening.

OUR SCIENTIFIC APPROACH AND STRATEGIC VISION

CrystalsFirst is committed to the constant improvement and expansion of its technology platform to better unlock the strategic advantages of structure- and fragment-based drug discovery.

Our technology renders complex trial & error approaches obsolete, ascertains the druggability of a given target, and ensures early and unambiguous identification of binders by crystallographic analysis.

Team

Dr. Serghei Glinca, MBA

Dr. Serghei Glinca, MBA

Chief Executive Officer

Dr. Stefan Merkl

Dr. Stefan Merkl

Chief Scientific Officer

Bernd Scheld

Bernd Scheld

Chief Financial Officer

Christian Rötz

Christian Rötz

Chief Operations Officer

Dr. Janis Müller

Dr. Janis Müller

Principal Scientist

Moritz Ruf

Moritz Ruf

Principal Scientist

Anna Trodler

Anna Trodler

Research Intern

Scientific Advisory Board

Prof. Dr. Gerhard Klebe

Prof. Dr. Gerhard Klebe

Philipps University Marburg

Dr. Gerhard Müller

Dr. Gerhard Müller

Gotham Therapeutics New York

Dr. Manfred S. Weiss

Dr. Manfred S. Weiss

Helmholtz Zentrum Berlin

CrystalsFirst GmbH
Marbacher Weg 6 | 35037 Marburg
Germany